Oxiracetam Review

Oxiracetam is a nootropic compound which benefits focus and acuity. 3, which is also referred to as 2-(4-hydroxy-2-oxopyrrolidin-1-yl)acetamide, is a member of the racetam family of nootropics.

Oxiracetam is one of the first derivatives of Piracetam to be discovered and synthesized. Even given the long amount of time it’s been around for compared to the novel racetam derivatives, little research has been done on its mechanisms and effects .

Human studies have shown that Oxiracetam is likely incredibly safe, and is not toxic even when consumed in large doses over long periods of time.

Rat and human studies have shown that Oxiracetam can protect against amnesia caused by scopolamine and other deliriants. This is due to it’s cholinergic activity, which preserves adequate levels of acetylcholine in the brain.

In addition to this Oxiractam stimulates both AMPA receptors, and NDMA receptors.

You should always consult a doctor before using a new nootropic.

Reported Effects


  • Stimulation
  • Improved concentration
  • Learning enhancement
  • Sensory enhancement


  • Increased stress
  • Irritability
  • Headaches
  • Nausea
  • Oxiracetam Dosage

Oxiracetam Dosage

The average dosage of Oxiracetam  is 500-2500mg over the course of the day.

I recommend you do not exceed 800mg per dose, as this will greatly increase your likelihood of negative side effects, and is not likely to yield increased benefits. Your experience may vary.

Like with all substances you should start at the lower end of the dosage spectrum in order to get an idea of your susceptibility to it, and slowly work your way up based on the effects you get. This method, known as dosage titration helps to minimize the risk of negative side effects, and should be practiced with all nootropics.

If you want to combine it with other nootropics, wait until you have settled on an Oxiracetam dosage which works for you. Whenever you are trying a new stack always dose each substance lower than you would individually, because certain nootropics potentiate each other.

Consumption Methods

There are two main ways that you can consume Oxiracetam.

1. Mix with water

Simply dump your Oxiracetam into a cup of water (or the fluid of your choice, whatever that may be), give it a little shake, and chug that shit!

Oxiracetam has a strong chemical taste, and I’m very sensitive to nasty flavors, so I prefer the latter method.

2. Parachute it

First take a square of toilet paper and rip it into a size that will fit the powder which you weighed. Then you want to split the piece of toilet paper which you have into two separate plies. This part can be a bit tricky, but usually inserting a fingernail in between works well.

When I parachute other, heavier nootropics I generally do not split the toilet paper into two separate plies, but given that Oxiracetam is so light I do. It makes it much easier to swallow.

Jam your little pile of powder smack dab in the middle, and wrap the corners of the toilet paper square up to the center. Then you want to twist the ends together so it forms a little package, and lightly wet the tip so it stays together.

Now you simply take your little bundle of fun, place it on your tongue, and wash it down with some water

Oxiracetam  Stacks


Choline is an important addition to any racetam stack.

Like the other members of the racetam family Oxiracetam increases levels of acetylcholine in the brain. This is a good thing, because this mechanism is responsible for most of it’s super sexy effects. However, if you do not adequately supplement choline you may end up with choline fatigue, which can be attributed to most of the negative side effects you may get from Oxiracetam.

Choline is a must.


This is a very good stack stack.

Many people find that the energy and stimulation from Oxiracetam synergizes well with the increased focus and verbal fluidity of Piracetam.

This stack can be a bit overstimulation for some people, so start on the lower end of the dosage spectrum


This stack is quite variable.

Both of these nootropics are pretty hit and miss in how they effect people, so this stack isn’t guaranteed to beneficial to you.

I have read some glowing reports about this combo, and some other not-so-glowing reports. Nootropics and the way which they effect you is something highly individual.

The only way to know is to try both of these substances yourself.

My Experience

My first experience with Oxiracetam I took 600mg with 600mg of choline. I did some studying while it kicked in, and then went to spend some time with a friend.

As we were driving, a knot of stress started to form in my chest. For anyone whose had a panic attack before, it was sort of like that.

My friend and I always discuss politics – him being a Reagan conservative, and me being a Bernie Sanders liberal. We normally casually joke around and make fun of eachother’s political opinions, but it’s all in good fun.

After having ingested Oxiracetam, that was not the case. I continuously interrupted my friend in the middle of him talking “You don’t understand, the free market doesn’t work” I would angrily exclaim. This went on for about an hour, and my mood remained the same even when we were not discussing politics.

All in all, I was a complete asshole to him. Thankfully he was understanding when I explained to him my predicament.

Since then I have experimented with lower doses in a secluded setting with the purpose of increasing productivity. I haven’t gotten any great benefits from this, and for me it causes stress even in low doses.

Aniracetam and Noopept effect me much better, therefore they are what I now use instead.


I have read reports of people having very good experiences with Oxiracetam, and others of people having poor experiences (like my own). Like with most nootropics it is really a matter of how Oxiracetam effects you as an individual.

If you are looking for a nootropic to increase your energy, focus and learning capability for work and study, then Oxiracetam is a good option.

The only way to know is to try Oxiracetam yourself – it may give you wonderful benefits.

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